The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants.

The double-edged role of copper in the fate of amyloid beta in the presence of anti-oxidants† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01787a Click here for additional data file.

P135: The Role of Amyloid Beta-Peptides and Tau Protein in Alzheimer\'s Disease

Alzheimer's desease is the most common age-related neurodegenerative disorder, and cognitive problems such as defects in learning and memory are of its symptoms.  Among the factors involved in the pathogenesis of the disease are biochemical disorders in protein production, oxidative stress, decreased acetylcholine secretion and inflammation of the brain tissue. Extra-neuronal accumulation ...

Involvement of TRPM7 calcium channels and PI3K/AKT kinase pathway in protective effect of vascular endothelial growth factor in amyloid beta-induced model of Alzheimer’s disease

Background and Objective: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, in which cortical and hippocampus neurons death is the main target of neurodegeneration. In addition to extracellular beta amyloid accumulation and the production of neural tangles, one of effective factors in the pathology of Alzheimer's disease is vascular injury in the elderly including disturbanc...

Effect of Fennel Extract on the Improvement of Memory Disorders in Beta Amyloid Alzheimer Model of Male Wistar Rats

Introduction: Alzheimer's disease is the most common neurodegenerative disorder. Due to the neurodegenerative effect of fennel (Foeniculum vulgare) this study aimed at investigating the effect of this plant on the improvement of learning and memory in rat models of Alzheimer's disease. Material & Methods: The male Wistar rats were assigned into six groups, namely the control group (no i...

P 131: Connection Process Inflammation and Improvement Alzheimer’s Disease

Platelet aggregation beta amyloid main causes inflammation of neurons in Alzheimer’s disease. In fact, creating this inflammation due to inappropriate actions in blood brain barrier (BBB) and astrocyte and microglia during the last century that studies conducted in this case nothing has been found. The only thing that can be done to prevent and reduce pro-inflammatory factors such as cyto...